Purple or violet flowers are found in scorpioid cymes. 1-1240, Vol. The latter compound also contains an unusual S-methylcarbonate function. ... Paederia foetida L. . They are used to increase infertility and treat paralysis. The northeastern region of India constitutes one of the biodiversity hotspots of the world. P. foetida has (sub)globose fruits and a very wide distribution in South-East Asia while P. cruddasiana Prain has laterally compressed-ovoid fruits, which are distinctly winged, and which occurs from northern India, Bangladesh, Nepal, Bhutan to south-western China and Thailand. Damage to the tissue releases an enzyme which splits off this sulphur-containing group from paederoside, and is therefore responsible for the unpleasant odour. MEDICINAL VALUES OF SKUNK VINE (Paederia foetida L.)-AN OVERVIEW Micropropagation of a few important medicinal plants. De, S., Ravishankar, B. The LDso of a 50% ethanolic extract of leaves was 1200 mg/kg in mice. They are commonly used for the treatment of intestinal complaints such as abdominal pain, colic, cramps, flatulence and dysentery; and are also used for treating rheumatism and gout [. The stem yields a strong and silky fibre, but it is not commercially exploited. P. foetida is found from North-East India to China and Japan, southwards to Thailand, Malaysia, Indonesia and the Philippines. The genus Paederia L.: a multidisciplinary study. There is very limited evidence to … The leaf and stem contain sitosterol, stigmasterol and campesterol. P foetida is also reported to have ethno medicinal uses … CONCLUSION: The available scientific research on Paederia foetida has shown that it is an important medicinal plant used in a wide range of ethnomedical treatments, especially for constipation, stomachache, dysentery, blood disorders, broken or fractured bones and sprains. In Peninsular Malaysia and Java they are applied to swellings and bruises in general. "P. foetida is mainly propagated by seed." The leaves of P. foetida are widely used in Asia and South-East Asia for the treatment of intestinal complaints such as colic, cramps, flatulence, dysentery and also for rheumatism and gout. It is a host for the root-knot nematode Meloidogyne sp. In India, the juice of the root is also prescribed in piles, inflammation of the spleen, and pain in the chest and liver. For intestinal problems, fresh leaves are pounded, water added, and the … Found in the Himalayas from Dehradun eastwards, up to an altitude of 1800 m. It is also found in Bihar, Orissa, Bengal and Assam. Monoterpenes such as linalol constitute the major components in the oil. pp. Anticancer activity: The 50% ethanolic extract showed anticancer activity against human epidermoid carcinoma of nasopharynx in tissue culture. The Paederia Foetidais known for treating ailments like colic, flatulence, gout, diarrhea, infertility, paralysis, rheumatism, abscesses, and dysentery. This fraction produced a significant inhibition of granulation tissue formation in cotton-pellet implanted rats. The antioxidant activity of fresh and dried plant extracts of Paederia foetida and Syzygium aqueum were studied using β-carotene bleaching and the 2,2’-azinobis(3-ethyl-benzothiazoline-6-sulfonic acid) (ABTS) radical cation assay. Merr. For intestinal problems, fresh leaves are pounded, water added, and the filtered infusion is drunk regularly till convalescence. The most abundant sulphur-containing compound was dimethyl disulphide. Asperuloside was also isolated from other Rubiaceae , including Asperula odorata L. and several Coprosma species. Ayurvedic medicine with Paederia foetida- Prasarini Thailam – used in arthritis, sciatica etc. 1 (A-H) pp. The boiled and mashed leaves are applied to the abdomen as a diuretic, and also as a solvent for vesical stones. It has been introduced into North America (North Carolina, Texas, Louisiana), Hawaii, Christmas Islands, Mauritius and Reunion as an ornamental and escaped. P. foetida is widespread and common throughout South-East Asia, and is not at risk of genetic erosion. The hepatoprotective potential of a leaf methanol extract has been assessed against CCl4-induced liver damage in the rat model. Embelin has been isolated from the aerial parts. It is extensively used in … In Ayurveda, the plant is used for treatment of arthritis, disorders of heart and kidney and it also serves as a widely used pain relieving massage oil. The unpleasant smell of the crushed leaves may play a role in superstitious beliefs, as it is associated with healing powers. The plant is considered specific for treating rheumatism and all types of neurological diseases. The percentage of antioxidant activity for all extract samples using both assays was between 58 and 80%. Nguyen Van Duong, 1993. Single intraperitoneal injection (IP) of streptozotocin (60 mg/kg body weight) was used for induction of diabetes is swiss albino (wistar strain) rats. Trichostrongylus and Haemonchus spp. It reduced the degradation changes in the articular cartilage induced by ananase and in vitro studies using ananase-treated chick embryonic bones showed that the plant (at a dose of 10 mg/ml of the medium) enhanced the growth of the chick bones cultivated in this medium. Ministry of Agriculture and Co-operatives, Kuala Lumpur, Malaysia. 2 volumes. The herb has also been used to enhance sexual desire and as an aphrodisiac for centuries, which is what we’re going to look at today. Fruit a drupe, (sub)globose, 4-6 mm in diameter, walls thin, dry, brittle, crowned by the persistent sepals, shiny pale brown to yellowish- or reddish-brown; pyrenes 2, semi-orbicular or semi-ellipsoidal, plano-convex or compressed, slightly smaller than fruit, without conspicuous wings, black, often conspicuously covered with raphides. Among the less-studied plants, Paederia foetida has been used by various ethnic tribes as food and medicine. Publications and Information Directorate, New Delhi, India.236, 250, 264, 331, 407, 552, 786, 788, 803, 810, 841, 926, 1076. In the carrageenan pleurisy test in rats, it reduced the pleural exudate volume and inhibited the migration of leucocytes into the inflammatory site. The leaves, in the form of a poultice, are applied to the abdomen to . Vietnam: dây mơ lông, dây mơ tròn, mơ tam thể. Paederia foetida L. (Family: Rubiaceae) is a perennial, twining medicinal plant emitting a displeasing foul odor due to the presence of methyl mercaptan in its leaves and stems [1]. Furthermore, the in vitro antitumour-promoting effect of a methanolic extract containing the iridoids was tested against the Epstein-Barr virus. The wealth of India: a dictionary of Indian raw materials & industrial products. Investigation of the anti-inflammatory effects of Paederia foetida. Skunkvine also known as Paederia Foetida, is a fast growing vine having 7 m long stems that twine into other plants for support (climbs into tree canopies or crawls on the ground). Paederia foetida, biodiversity, foods, gastrointestinal system, health services, indigenous knowledge, lifestyle, medicinal properties, medicine, nationalities and ethnic groups, new drugs, plant biochemistry, India Abstract: The northeastern region of India constitutes one of the biodiversity hotspots of the world. In India and Indo-China, the stem, leaves and seeds are applied specifically for rheumatism, alone or in mixtures with other plants. Vol. Inhibitory effect of iridoids on Epstein-Barr virus activation by a short-term in vitro assay for anti-tumor promoters. Kapadia, G.J., Sharma, S.C., Tokuda, H., Nishino, H. & Ueda, S., 1996. & Srivastava, T.N., 1994. It also decreased liver (but not serum) aspartate transaminase activity but did not affect adrenal weight and ascorbic acid content significantly. Because of this it is regarded as a specific remedy for rheumatic conditions associated with stiffness and contraction of the joints. Antiarthritic activity: Paederia foetida extract was tested for its effect on osteoarthritis-like lesions induced in the knee joints of rabbits by ananase (the proteolytic enzyme from pineapple). In the Philippines, the bark or the root is considered emetic, and the leaves are used in antirheumatic baths. Gandha means, smell and prasarini means spreading. Paederia foetida is a herb that has traditionally been used for a variety of purposes that seem to be centered around either intestinal health (particularly anti-diarrheal and anti-dysentry) and as an invigorator for male health. Fitoterapia 65(4): 357-362. The results also demonstrate that the plant extract possesses cytotoxic activities. It may help to eliminate poisons collected in the system. P. foetida is harvested from the wild whenever needed. Paederoside showed a similar inhibitory activity to that of asperuloside and daecetyl-asperulosidic acid in a plant growth inhibition test and in an antimicroorganism activity test. Mekong Printing, Santa Ana, California, United States. Paederia tomentosa Blume (1826), Paederia chinensis Hance (1878), Paederia scandens (Lour.) Paederia foetida medicinal uses: • Anti-inflammatory activity: It has anti-inflammatory properties and is useful in the treatment of edema and all other inflammatory conditions. The leaves are also used to treat hepatic disorders and rheumatism. Medicinal Uses. Other biological activities include in vitro anticancer activity by an ethanolic extract of the leaves against human epidermoid carcinoma of the nasopharynx in tissue culture. (1934). 147. asperuloside, scandoside and paederoside were isolated from the aerial parts of P. foetida . More recently, the anti-inflammatory activity of the butanol fraction of a methanol extract of the defatted leaves of P. foetida was tested. As per the properties and functions of the herb it is used in healing the problems related to intestinal health (particularly anti-diarrheal and anti-dysentery) and as a support for male health. Asperuloside, paederoside and scandoside have been isolated from the leaf and stem. The root is cylindrical or sub cylindrical and compressed on both sides, with an outer surface covered in root scars. 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