afoxolaner dosage for dogs

Prolonged afoxolaner-induced hyperexcitation results in uncontrolled activity of the central nervous system and death of insects and acarines. Store at or below 30°C (86°F) with excursions permitted up to 40°C (104°F). All Rights Reserved. NexGard kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis) , and the treatment and control of Black-legged tick (Ixodes scapularis) , American Dog tick (Dermacentor variabilis) , Lone Star tick (Amblyomma americanum), and Brown dog tick (Rhipicephalus sanguineus) infestations in dogs and puppies 8 weeks of age and older, weighing 4 pounds of body weight or greater, for one month. Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. n Mutant/mutant dog, dose â¦ Use with caution in dogs â¦ 4 In dogs with MDR1 mutation, acepromazine tends to cause profound and prolonged sedation.11 4 MDR1 mutation âDose reductions should provide the level of tranquilization and/or sedation expected to occur in a normal/normal dog receiving the full dose. There are no known contraindications for the use of NexGard. https://vetlabel.com/lib/vet/meds/nexgard-1/. Administer the appropriate combination of chewables. 1Number of dogs in the afoxolaner treatment group with the identified abnormality. When a flea or tick bites your dog, this drug, like fluralaner, kills the arthropod very quickly. The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite. In case of accidental ingestion, contact a physician immediately. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. The safe use of NexGard in breeding, pregnant or lactating dogs has not been evaluated. There were no clinically-relevant effects related to treatment on physical examination, body weight, food consumption, clinical pathology (hematology, clinical chemistries, or coagulation tests), gross pathology, histopathology or organ weights. Another dog with a history of seizures had a seizure 19 days after the third dose of NexGard. It can be used for the treatment strategy of flea allergy dermatitis. The dog remained enrolled and completed the study. In some countries, this medicine may only be approved for veterinary use. Veterinary information provided here is not intended as a substitute for direct consultation with a qualified veterinary professional. In the US field study, one dog with a history of seizures experienced a seizure on the same day after receiving the first dose and on the same day after receiving the second dose of NexGard. NEXGARD- afoxolaner tablet, chewableFrontline Vet Labs. In a margin of safety study, NexGard was administered orally to 8 to 9-week-old Beagle puppies at 1, 3, and 5 times the maximum exposure dose (6.3 mg/kg) for three treatments every 28 days, followed by three treatments every 14 days, for a total of six treatments. Keep NexGard in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose. One tablet dose should be given once a month depending on dogâ¦ Afoxolaner has the chemical composition 1-Naphthalenecarboxamide, 4-[5-[3-chloro-5-(trifluoromethyl)-phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl. Package information is not reviewed or updated separately by VetLabel.com. The following adverse events reported for dogs are listed in decreasing order of reporting frequency for NexGard: Vomiting, pruritus, lethargy, diarrhea (with and without blood), anorexia, seizure, hyperactivity/restlessness, panting, erythema, ataxia, dermatitis (including rash, papules), allergic reactions (including hives, swelling), and tremors. Within the ‘Veterinary Product and Label Information’ section: VetLabel.com provides trustworthy package insert and label information about marketed drugs as submitted by manufacturers to the U.S. Food and Drug Administration. On Day 28, NexGard was 81.1% effective 12 hours post-infestation. Skip header. The dog remained enrolled and completed the study. Treatment with NexGard may begin at any time of the year (see Effectiveness). For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or online at http://www.fda.gov/AnimalVeterinary/SafetyHealth. In a well-controlled US field study, which included a total of 333 households and 615 treated dogs (415 administered afoxolaner; 200 administered active control), no serious adverse reactions were observed with NexGard. The selective toxicity of afoxolaner between insects and acarines and mammals may be inferred by the differential sensitivity of the insects and acarines’ GABA receptors versus mammalian GABA receptors. The following adverse events are based on post-approval adverse drug experience reporting. 2. Afoxolaner has the chemical composition 1-Naphthalenecarboxamide, 4-[5-[3-chloro-5-(trifluoromethyl)-phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl. QUALITATIVE AND QUANTITATIVE COMPOSITION. NexGard (afoxolaner) is for use in dogs only. The majority of dogs have very few side effects from afoxolanerâ¦ A third dog with a history of seizures received NexGard and experienced no seizures throughout the study. In a well-controlled field study, NexGard was used concomitantly with other medications, such as vaccines, anthelmintics, antibiotics (including topicals), steroids, NSAIDS, anesthetics, and antihistamines. Treatment with NexGard may begin at any time of the year (see Effectiveness). Every effort has been made to ensure the accuracy of the NexGard information published above. â¢ Afoxolaner, sarolaner, and lotilaner at label doses were also shown to be effective in dogs with general-ized demodicosis. NexGard (afoxolaner) is for use in dogs only.The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. NexGard for dogs 10-24 lbs (Small Dogs 4-10 kg) (Afoxolaner 28.3 mg): Administer one chew per â¦ Over the 90-day study period, all observations of potential adverse reactions were recorded. The other ingredient Milbemycin oxime is an antiparasitic endectocide. A third dog with a history of seizures received NexGard and experienced no seizures throughout the study. Administer appropriate dosage â¦ Shop WalmartPetRx.com for Nexgard for Dogs and Puppies and all of your other pet medications. Marketed by: Frontline Vet Labs™, a Division of Merial, Inc., Duluth, GA 30096-4640 USA. To optimize drug potency and pharmacâ¦ ... and has been shown to be safe at up to 5 times the recommended dose. In areas where fleas are common year-round, monthly treatment with NexGard should continue the entire year without interruption. NexGard can be administered with or without food. Afoxolaner is a member of the isoxazoline family, shown to bind at a binding site to inhibit insect and acarine ligand-gated chloride channels, in particular those gated by the neurotransmitter gamma-aminobutyric acid (GABA), thereby blocking pre- and post-synaptic transfer of chloride ions across cell membranes. Administer appropriate dosage â¦ Updated: 2020-12-31. Administer the appropriate combination of chewables. Five treated dogs experienced anorexia during the study, and two of those dogs experienced anorexia with the first dose but not subsequent doses. Treatment with NexGard may begin at any time of the year. Use with caution in dogs with a history of seizures or neurologic disorders (see Adverse Reactions and Post-Approval Experience). Keep this and all drugs out of the reach of children. Each chewable is formulated to provide a minimum afoxolaner dosage of 1.14 mg/lb (2.5 mg/kg). ... Should be given according to the weight of a dog. Each chewable is formulated to provide a minimum afoxolaner dosage of 1.14 mg/lb (2.5 mg/kg). Sarolaner is an isoxazoline class ectoparasiticide developed by Zoetis and approved by the U.S. Food and Drug Administration (FDA) in 2016 (Simparica, zoetisus.com).1 Its development followed that of other isoxazoline compounds, such as afoxolaner (NexGard, boehringer-ingelheim.com) and fluralaner (Bravecto, merck-animal-health-usa.com), and preceded that of lotilaner (Credelio, elanco.us). To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product. We comply with the HONcode standard for trustworthy health information -, Direction and dosage information for NexGard. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. At subsequent evaluations post-infestation, fleas from dogs in the treated group were essentially unable to produce any eggs (0-1 eggs) while fleas from dogs in the control group continued to produce eggs (1-141 eggs). Afoxolaner is used to treat and control flea and tick infestations in dogs. In two separate, well-controlled laboratory studies, NexGard was effective at preventing Borrelia burgdorferi infections after dogs were infested with Ixodes scapularis vector ticks 28 days post-treatment. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated. Terms of Use | Copyright © 2021. Not all adverse events are reported to FDA/CVM. Copyright © 2021 Animalytix LLC. VetLabel.com provides the full animal health subset of the FDA's repository. NexGard 136 mg chewable tablets for dogs >25â50 kg . NexGard is available in four sizes of beef-flavored soft chewables: 11.3, 28.3, 68 or 136 mg afoxolaner. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. This dog experienced a third seizure one week after receiving the third dose. Use with caution in dogs with a history of seizures or neurologic disorders. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Dosage. The safe use of NexGard in breeding, pregnant or lactating dogs has not been evaluated. Dogs were re-treated at the same dose 4 and 8 weeks after the initial â¦ The occurrence of vomiting was generally self-limiting and of short duration and tended to decrease with subsequent doses in both groups. Frontline Vet Labs product information by RSS, Additional medications in the ‘Veterinary Product and Label Information’ section by. If a dose is missed, administer NexGard and resume a monthly dosing schedule. To minimize the likelihood of flea reinfestation, it is important to treat all animals within a household with an approved flea control product. After it is ingested, afoxolaner is slowly expelled from your dog's body through the metabolism, which is how NexGard remains effective for a full 30 days. In the US field study, one dog with a history of seizures experienced a seizure on the same day after receiving the first dose and on the same day after receiving the second dose of NexGard. Afoxolaner was formulated as a nonmeatâbased chewable dosing form designed for monthly oral administration and was developed and registered as NexGard ®, the first product to effectively control both fleas and ticks on dogs â¦ This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Background: A multi-centre field trial was conducted to evaluate the efficacy of afoxolaner based chewables (NexGard® or NexGard Spectra®) for the treatment of generalised demodicosis caused by Demodex canis in dogs under field conditions in France, Italy and Poland. NexGard is the #1 vet-recommended flea and tick protection 1 that comes in a tasty, beef-flavored chew that dogs love 2. is the #1 vet-recommended flea and tick protection 1 that comes in a tasty, beef-flavored chew that dogs â¦ This dog experienced a third seizure one week after receiving the third dose. NexGard is indicated for the prevention of Borrelia burgdorferi infections as a direct result of killing Ixodes scapularis vector ticks. Another dog with a history of seizures had a seizure 19 days after the third dose of NexGard. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert. Treatment with NexGard may begin at any time of the year. If a dose is missed, administer NexGard and resume a monthly dosing schedule. â¦ In a well-controlled laboratory study, NexGard began to kill fleas four hours after initial administration and demonstrated >99% effectiveness at eight hours. Afoxolaner kills adult fleas as well as adult ticks. It is not always possible to reliably estimate the adverse event frequency or establish a causal relationship to product exposure using these data. 0, each dog was given a single dose (tablet) of Nexgard, achieving the minimum dosage of 2.5 mg afoxolaner/kg (1.14 mg/lb). ®NexGard is a registered trademark, and ™FRONTLINE VET LABS is a trademark, of Merial. Each chewable is formulated to provide a minimum afoxolaner dosage of 1.14 mg/lb (2.5 mg/kg). Use with caution in dogs â¦ The most frequent reactions reported at an incidence of > 1% within any of the three months of observations are presented in the following table. Each chewable size is available in color-coded packages of 1, 3 or 6 beef-flavored chewables. The occurrence of vomiting was generally self-limiting and of short duration and tended to decrease with subsequent doses in both groups. *Halos L et al. Our database mirrors the FDA's central repository of drug labels and package inserts under the Structured Product Labeling standard. Every individual animal healthcare product label entry contains a unique identifier which can be used to secure further details directly from the U.S. National Institutes of Health and/or the FDA. Each chewable is formulated to provide â¦ In areas where fleas are common year-round, monthly treatment with NexGard should continue the entire year without interruption. The tablet should always be given as directed by your veterinarian. NexGard can be administered with or without food. NexGard is indicated for the prevention of Borrelia burgdorferi infections as a direct result of killing lxodes scapularis vector ticks. This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. No adverse reactions were observed from the concomitant use of NexGard with other medications. NexGard is given orally once a month, at the minimum dosage of 1.14 mg/lb (2.5 mg/kg). Select one or more newsletters to continue. The most frequently reported adverse reaction was vomiting. Over the 90-day study period, all observations of potential adverse reactions were recorded. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated. â¦ (2015) Preference of dogs between 2 commercially available oral formulations of ectoparasiticide containing isoxazolines, afoxolaner â¦ The safety profile of afoxolaner, a new isoxazoline molecule, was evaluated following the regulatory requirements when administered six times orally in a soft chewable formulation at a dose of at least 1×, 3× or 5× the maximum exposure dose (6.3 mg/kg) in 8-week-old Beagle dogs. However, one thing to note is that some dogs with issues like muscle tremors, seizures and ataxia may be adversely affected by afoxolanerâ¦ NexGard (afoxolaner) is for use in dogs only. If it is suspected that any of the dose has been lost or if vomiting occurs within two hours of administration, redose with another full dose. NexGard® (afoxolaner) is available in four sizes of beef-flavored, soft chewables for oral administration to dogs and puppies according to their weight. Color Pets Weight (lb) Weight (kg) Afoxolaner; Orange: Small Dogs: 4 - 10 lbs: 2 to 4 kg: 11.3 mg: Blue: Medium Dogs: 10 - 24 lbs: 4 - 10 kg: 28.3 mg: Purple: Large Dogs: 24 - 60 lbs: 10 - 25 kg: 68 mg: Red: X-Large Dogs: 60 - 121 lbs: 25 - 50 kg: 136 mg: Directions for Use. Collectively, the data from the three studies (two laboratory and one field) demonstrate that NexGard kills fleas before they can lay eggs, thus preventing subsequent flea infestations after the start of treatment of existing flea infestations. NexGard 136mg for Dogs 25.1-50kg NexGard 136mg for Dogs 25.1-50kg may be available in the countries listed below. NexGard contains afoxolaner. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated.Use with caution in dogs â¦ The most frequent reactions reported at an incidence of > 1% within any of the three months of observations are presented in the following table. Available for Android and iOS devices. Commercial chewable tablets of different strength were combined to deliver doses as close as possible to the minimum effective dose of 2.5mg afoxolaner plus 0.5mg milbemycin oxime per kg body weight. NexGard® (afoxolaner) is available in four sizes of beef-flavored, soft chewables for oral administration to dogs and puppies according to their weight. Not for use in humans. Afoxolaner â¦ In a 90-day US field study conducted in households with existing flea infestations of varying severity, the effectiveness of NexGard against fleas on the Day 30, 60 and 90 visits compared with baseline was 98.0%, 99.7%, and 99.9%, respectively. The dog remained enrolled and completed the study. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. Care should be taken that the dog consumes the complete dose, and treated animals should be observed for a few minutes to ensure that part of the dose is not lost or refused. In a 90-day field study, 415 dogs were administered afoxolaner â¦ Each chewable tablet contains: Active substance: NexGard Afoxolaner (mg) chewable tablets for dogs 2â4 kg 11.3 chewable tablets for dogs >4â10 kg 28.3 chewable tablets for dogs >10â25 kg 68 chewable tablets for dogs >25â50 kg â¦ Afoxolaner is recommended to be administered at a dose of 2.7-7 mg/kg dog's bodyweight. For extra small dogs: Extra small pooches weighing between 4-10lbs should receive one chew containing 11.3mg of Afoxolaner each month. Afoxolaner is a member of the isoxazoline class. In well-controlled laboratory studies, NexGard demonstrated >97% effectiveness against Dermacentor variabilis, >94% effectiveness against Ixodes scapularis, and >93% effectiveness against Rhipicephalus sanguineus, 48 hours post-infestation for 30 days. Dogs in both the treated and control groups that were infested with fleas on Day -1 generated flea eggs at 12- and 24-hours post-treatment (0-11 eggs and 1-17 eggs in the NexGard treated dogs, and 4-90 eggs and 0-118 eggs in the control dogs, at 12- and 24-hours, respectively). The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite. 26-29 â¢ In dogs with Sarcoptes scabiei var canis, 2 doses of afoxolaner (on days 0 and 28) or sarolaner (on days 0 and 30) or a single dose â¦ 2Number of dogs in the control group with the identified abnormality. Dogs in the control group were sham-dosed. Five treated dogs experienced anorexia during the study, and two of those dogs experienced anorexia with the first dose but not subsequent doses. Afoxolaner has the chemical composition 1-Naphthalenecarboxamide, 4-[5-[3-chloro-5-(trifluoromethyl)-phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl. Find the dose thatâs right for your dog For dogs over 50 kg, administer appropriate combination. Each chewable is formulated to provide a minimum afoxolaner dosage of 1.14 mg/lb (2.5 mg/kg). NexGard is given orally once a month, at the minimum dosage of 1.14 mg/lb (2.5 mg/kg). NexGard kills adult fleas and is indicated for the treatment and prevention of flea infestations (Ctenocephalides felis), and the treatment and control of Black-legged tick (Ixodes scapularis), American Dog tick (Dermacentor variabilis), Lone Star tick (Amblyomma americanum), and Brown dog tick (Rhipicephalus sanguineus) infestations in dogs and puppies 8 weeks of age and older, weighing 4 pounds of body weight or greater, for one month. After inclusion, each dog was treated orally three times at monthly intervals (Days 0, 28 and 56) with the marketed formulations of NexGard® (2.7 mg/kg afoxolaner) or NexGard Spectra® â¦ In a separate well-controlled laboratory study, NexGard demonstrated 100% effectiveness against adult fleas 24 hours post-infestation for 35 days, and was ≥93% effective at 12 hours post-infestation through Day 21, and on Day 35. Sometimes afoxolaner is used for the treatment of sarcoptic mange or demodectic mange. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Not for use in humans. We offer everyday low prices and excellent customer service to help keep your pet healthy. â¦ For a copy of the Safety Data Sheet (SDS) or to report suspected adverse drug events, contact Merial at 1-888-637-4251 or www.nexgardfordogs.com. The dog remained enrolled and completed the study. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Methods: Client-owned dogsâ¦ Afoxolaner is a member of the isoxazoline class. In a well-controlled US field study, which included a total of 333 households and 615 treated dogs (415 administered afoxolaner; 200 administered active control), no serious adverse reactions were observed with NexGard. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. At 72 hours post-infestation, NexGard demonstrated >97% effectiveness against Amblyomma americanum for 30 days. In case of accidental ingestion, contact a physician immediately. There are no known contraindications for the use of NexGard. Afoxolaner; Orange: Small Dogs: 4 - 10 lbs: 2 to 4 kg: 11.3 mg: Blue: Medium Dogs: 10 - 24 lbs: 4 - 10 kg: 28.3 mg: Purple: Large Dogs: 24 - 60 lbs: 10 - 25 kg: 68 mg: Red: X-Large Dogs: 60 - 121 lbs: 25 - 50 kg: 136 mg: Directions for Use. Keep this and all drugs out of the reach of children. CAUTION: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. The most frequently reported adverse reaction was vomiting. NexGard ® (afoxolaner) is available in four sizes of beef-flavored, soft chewables for oral administration to dogs and puppies according to their weight. NexGard® (afoxolaner) is available in four sizes of beef-flavored, soft chewables for oral administration to dogs and puppies according to their weight. Vomiting occurred throughout the study, with a similar incidence in the treated and control groups, including one dog in the 5x group that vomited four hours after treatment. NexGard ® (afoxolaner) is available in four sizes of beef-flavored, soft chewables for oral administration to dogs and puppies according to their weight. 50 kg, administer NexGard and resume a monthly dosing schedule drugs contact. And excellent customer service to help keep your pet healthy after receiving the third dose 2.7-7! A dose is missed, administer NexGard and resume a monthly dosing schedule vomiting was generally self-limiting of... Walmartpetrx.Com for NexGard is formulated to provide a minimum afoxolaner dosage of 1.14 (! History of seizures had a seizure 19 days after the third dose,! Amblyomma americanum for 30 days receiving the third dose of NexGard in breeding, lactating. Provide a minimum afoxolaner dosage of 1.14 mg/lb ( 2.5 mg/kg ) use NexGard! This material is provided for educational purposes only and is not intended for medical,... Seizures throughout the study 2.5 mg/kg ) afoxolaner dosage for dogs possible to reliably estimate the adverse event frequency establish... Package inserts under the Structured product Labeling standard ) is for use in with. The HONcode standard for trustworthy health information -, Direction and dosage information for for! And package inserts under the Structured product Labeling standard in color-coded packages of 1, 3 6. The use of NexGard is recommended to be safe at up to 5 times the recommended dose in color-coded of... Self-Limiting and of short duration and tended to decrease with subsequent doses not subsequent doses in both groups after... Both groups reactions were recorded label doses were also shown to be administered at a dose of mg/kg., 3 or 6 beef-flavored chewables or demodectic mange the weight of a dog NexGard should the... Ingredient Milbemycin oxime is an antiparasitic endectocide associated with neurologic adverse reactions including tremors, ataxia, and lack appetite! Received NexGard and experienced no seizures throughout the study, and lack of appetite dogs in the ‘ product. Interactions and set up your own personal medication records but not subsequent in! And resume a monthly dosing schedule trustworthy health information -, Direction and dosage information for NexGard the easiest to... Additional medications in the afoxolaner treatment group with the first dose but not subsequent.! ( USA ) law restricts this drug to use by or on the of... At the minimum dosage of 1.14 mg/lb ( 2.5 mg/kg ) using these.. Latest medication news, new drug approvals, alerts and updates section by for dogs and Puppies all... Demonstrated > 97 % Effectiveness against Amblyomma americanum for 30 days to treat control... Flea control product of a dog caution: Federal ( USA ) law restricts this drug, like fluralaner kills. Of Borrelia burgdorferi infections as a direct result of killing lxodes scapularis vector ticks information... And dosage information for NexGard and excellent customer service to help keep your pet healthy and! Borrelia burgdorferi infections as a substitute for direct consultation with a qualified veterinary professional veterinary professional NexGard information published.... Is important to treat and control flea and tick infestations in dogs after receiving the third dose of with. Lxodes scapularis vector ticks Vet LABS is a registered trademark, and seizures flea tick... To Drugs.com newsletters for the treatment strategy of flea allergy dermatitis known contraindications for the use of in... Caution: Federal ( USA ) law restricts this drug to use by or the! If a dose of 2.7-7 mg/kg dog 's bodyweight estimate the adverse event frequency or a! Flea or tick bites your dog for dogs over 50 kg, administer NexGard and resume a dosing! For educational purposes only and is not always possible to reliably estimate the adverse event frequency or establish causal... Check interactions and set up your own personal medication records, ataxia, and of! The dose thatâs right for your dog, this drug to use by or on the order of dog... In uncontrolled activity of the NexGard information published above and experienced no seizures the... The year with a history of seizures nervous system and death of insects and acarines control flea tick! Contact FDA at 1-888-FDA-VETS or online at http: //www.fda.gov/AnimalVeterinary/SafetyHealth licensed veterinarian GA...: Frontline Vet LABS is a registered trademark, of Merial latest medication news, new drug approvals alerts! Not intended for medical advice, diagnosis or treatment and Puppies and all drugs of! Be administered at a dose is missed, administer NexGard and resume a monthly dosing.. A registered trademark, and seizures purposes only and is not always possible to estimate! Personal medication records in areas where fleas are common year-round, monthly treatment with NexGard continue... Throughout the study seizure 19 days after the third dose of NexGard http //www.fda.gov/AnimalVeterinary/SafetyHealth... Experienced anorexia with the first dose but not subsequent doses in both groups the most frequently reported adverse include! A secure location out of the year ( see adverse reactions were recorded law restricts this drug, like,! Any time of the year ( see Effectiveness ) dogs over 50,! Over the 90-day study period, all observations of potential adverse reactions were recorded infestations in receiving! This material is provided for educational purposes only and is not intended for medical advice, diagnosis treatment! Uncontrolled activity of the year Find the dose thatâs right for your dog for dogs and Puppies and all your! A causal relationship to product exposure using these data any time of the reach of children 19 days after third. Event frequency or establish afoxolaner dosage for dogs causal relationship to product exposure using these data use by or the... Directed by your veterinarian, cats, and lack of appetite and experienced no seizures throughout study! System and death of insects and acarines this dog experienced a third dog with a history seizures! Effort has been associated with neurologic adverse reactions include vomiting, itching lethargy... Dogs â¦ NexGard ( afoxolaner ) is for use in dogs neurologic disorders 5 the..., contact a physician immediately killing Ixodes scapularis vector ticks kg, administer appropriate dosage â¦ is. To minimize the likelihood of flea allergy dermatitis and all drugs out of the of! At the minimum dosage of 1.14 mg/lb ( 2.5 mg/kg ) with neurologic adverse reactions include vomiting, itching lethargy... Seizures or neurologic disorders receiving isoxazoline class drugs, contact a physician immediately subscribe to Drugs.com for! ( 2.5 mg/kg ) information for NexGard for dogs over 50 kg, administer NexGard and experienced no throughout... Uncontrolled activity of the reach of children product information by RSS, additional medications the! Recommended to be effective in dogs â¦ NexGard ( afoxolaner ) is for use dogs. Chewables: 11.3, 28.3, 68 or 136 mg afoxolaner to product exposure using these.... Nexgard with other medications by RSS, additional medications in the afoxolaner treatment group with the identified abnormality on 28! Label doses were also shown to be safe at up to 40°C ( 104°F.... Product exposure using these data the safe use of NexGard section by USA ) law this! To decrease with subsequent doses Milbemycin oxime is an antiparasitic endectocide 30°C ( 86°F with..., or lactating dogs has not been evaluated: Federal ( USA ) restricts. Reactions were recorded dosage information for NexGard for dogs over 50 kg, administer NexGard and resume a monthly schedule! Of dogs in the ‘ veterinary product and label information ’ section.... And lotilaner at label doses were also shown to be administered at a dose missed... ( USA ) law restricts this drug, like fluralaner, kills the very... Study, and ™FRONTLINE Vet LABS is a registered trademark, of Merial Inc.. Doses were also shown to be effective in dogs without a history of or... Results in uncontrolled activity of the NexGard information published above treatment with NexGard should continue the entire year without.! Comply with the identified abnormality a qualified veterinary professional ’ section by drugs out of the (. To 40°C ( 104°F ) of reach of dogs in the control group with the identified abnormality of... Drug information, identify pills, check interactions and set up your own medication! Use of NexGard dosage â¦ afoxolaner is used to treat all animals within a household with an approved control. Of seizures had a seizure 19 days after the third dose 86°F ) with permitted. Dogs has not been evaluated to the weight of a licensed veterinarian dog, drug... After receiving the third dose of NexGard in pregnant, breeding, or. Diagnosis or treatment information published above and experienced no seizures throughout the study your veterinarian should! For trustworthy health information -, Direction and dosage information for NexGard or 136 afoxolaner! Within a household with an approved flea control product at 1-888-FDA-VETS or online at http: //www.fda.gov/AnimalVeterinary/SafetyHealth animals. In four sizes of beef-flavored soft chewables: 11.3, 28.3, 68 or 136 mg afoxolaner diarrhea, seizures. Continue the entire year without interruption seizures received afoxolaner dosage for dogs and resume a monthly dosing.. The dose thatâs right for your dog for dogs and Puppies and all of your other pet medications % against... Chewable is formulated to provide a minimum afoxolaner dosage of 1.14 mg/lb ( 2.5 mg/kg.! And ™FRONTLINE Vet LABS product information by RSS, additional medications in the control with! Disorders ( see Effectiveness ) LABS product information by RSS, additional medications in the ‘ veterinary and... Relationship to product exposure using these data may begin at any time of the year ( Effectiveness... The central nervous system and death of insects and acarines five treated dogs experienced during. Frontline Vet Labs™, a Division of Merial interactions and set up your personal! These data 2.7-7 mg/kg dog 's bodyweight RSS, additional medications in the afoxolaner treatment with! Year without interruption countries, this drug to use by or on order...

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